Methyl 2-[2-(benzyloxycarbonylamino)propan-2-yl]-5-hydroxy-6-methoxypyrimidine-4-carboxylate
2011
Crystal Structure of a Pyrimidine Derivative
publication
Evidence: moderate
Author Information
Author(s): Fun Hoong-Kun, Sumangala V., Prasad D. Jagadeesh, Poojary Boja, Chantrapromma Suchada
Primary Institution: Universiti Sains Malaysia
Hypothesis
The study aims to synthesize and report the crystal structure of a specific pyrimidine derivative.
Conclusion
The synthesized compound exhibits a unique crystal structure characterized by specific dihedral angles and hydrogen bonding interactions.
Supporting Evidence
- The dihedral angle between the benzene and pyrimidine rings is 52.26°.
- The carboxylate unit is twisted with respect to the pyrimidine ring, making a dihedral angle of 12.33°.
- Molecules are linked by O—H⋯O hydrogen bonds, forming an inversion dimer.
Takeaway
Scientists made a new chemical compound and looked at its structure using X-ray. They found interesting angles and how the molecules stick together.
Methodology
The compound was synthesized through a series of chemical reactions and characterized using X-ray crystallography.
Digital Object Identifier (DOI)
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