Relationship Between Atherogenic Index of Plasma and Uric Acid Levels
Author Information
Author(s): Huang Jingjing, Chen Chunhong, Jie Chunxiao, Li Ruying, Chen Chunyong
Primary Institution: The First Affiliated Hospital of Guangxi Medical University
Hypothesis
This study aimed to investigate the relationship between the atherogenic index of plasma (AIP) and serum uric acid (SUA) levels, as well as the risk of hyperuricemia.
Conclusion
The study found a significant L-shaped relationship between AIP and both uric acid levels and hyperuricemia prevalence, indicating a saturation effect beyond specific thresholds.
Supporting Evidence
- AIP was significantly associated with uric acid levels and hyperuricemia prevalence.
- The study identified specific thresholds for AIP beyond which the relationship with uric acid levels and hyperuricemia was not significant.
- The findings suggest that AIP could be a valuable marker for identifying individuals at risk of elevated uric acid levels.
Takeaway
This study shows that as the atherogenic index of plasma increases, the risk of high uric acid levels and hyperuricemia also increases, but only up to a certain point.
Methodology
A cross-sectional study using data from the National Health and Nutrition Examination Survey (NHANES) with weighted linear and logistic regression analyses.
Potential Biases
Potential recall bias from self-reported lifestyle factors and medical history.
Limitations
The cross-sectional design limits causal inference, and reliance on self-reported data may introduce bias.
Participant Demographics
Participants were adults aged 18 and above, with a diverse demographic including various races and socioeconomic statuses.
Statistical Information
P-Value
p<0.001
Confidence Interval
95% CI: 0.762, 0.946
Statistical Significance
p<0.001
Digital Object Identifier (DOI)
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