Successful Treatment of Osteomyelitis in a Child with HIV
Author Information
Author(s): Riordan Andrew I, Adalat Shazia, Graham Clive
Primary Institution: Birmingham Heartlands Hospital, UK
Hypothesis
What is the best treatment for antibiotic-resistant pneumococcal osteomyelitis in immunocompromised children?
Conclusion
The combination of rifampicin and azithromycin was effective and well tolerated for treating antibiotic-resistant pneumococcal osteomyelitis in a child with HIV.
Supporting Evidence
- The child had a normal wrist function 18 months after treatment.
- She remained on her original cART regimen with an undetectable viral load.
- The combination of rifampicin and azithromycin was well tolerated.
Takeaway
Doctors found that using two specific antibiotics together helped a sick baby with a bone infection caused by a tough germ, and she got better.
Methodology
The child was treated with parenteral teicoplanin, oral rifampicin, and azithromycin after being diagnosed with osteomyelitis.
Limitations
The study is based on a single case report, limiting generalizability.
Participant Demographics
A 6-month-old black African girl with HIV.
Digital Object Identifier (DOI)
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