PfGSTF2 endows resistance to quizalofop‐p‐ethyl in Polypogon fugax by GSH conjugation
2024

How a Plant Fights Herbicides

publication 10 minutes Evidence: high

Author Information

Author(s): Wen Chen, Bai Dingyi, Liao Yuxi, Yu Qin, Bai Lianyang, Pan Lang

Primary Institution: Hunan Agricultural University

Hypothesis

Weed GST confers herbicide resistance.

Conclusion

The study found that the PfGSTF2 gene plays a significant role in the resistance of Polypogon fugax to the herbicide quizalofop-p-ethyl through enhanced metabolism.

Supporting Evidence

  • Transgenic rice calli overexpressing PfGSTF2 showed resistance to quizalofop-p-ethyl.
  • CRISPR/Cas9 knockout of the orthologous gene in rice increased sensitivity to quizalofop-p-ethyl.
  • Recombinant PfGSTF2 detoxified quizalofop acid, generating less harmful metabolites.

Takeaway

Plants can become resistant to herbicides by using special proteins to break them down, making them less harmful.

Methodology

The study involved cloning and characterizing GST genes, transgenic rice experiments, and in vitro herbicide metabolism analysis.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1111/pbi.14491

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