Biological and Cellular Effects of Percutaneous Electrolysis: A Systematic Review
Author Information
Author(s): Rodríguez-Sanz Jacobo, Rodríguez-Rodríguez Sergi, López-de-Celis Carlos, Malo-Urriés Miguel, Pérez-Amodio Soledad, Pérez-Antoñanzas Román, Borrella-Andrés Sergio, Albarova-Corral Isabel, Mateos-Timoneda Miguel Ángel
Primary Institution: International University of Catalonia
Hypothesis
The objective of this article is to evaluate the biological and cellular effects of percutaneous electrolysis and its influence on tissue healing processes.
Conclusion
Percutaneous electrolysis generates a controlled local pro-inflammatory effect in chronic conditions and regulates inflammation in inflammatory injuries during the first 7 days.
Supporting Evidence
- Percutaneous electrolysis generates a significant pro-inflammatory increase in chronic tendon conditions.
- A significant increase in cell death markers was observed during the first 7 days.
- Electrolysis facilitates subsequent healing by improving extracellular matrix synthesis starting from 7 days after application.
Takeaway
Percutaneous electrolysis is a treatment that can help heal injuries by causing a little inflammation at first, which helps the body repair itself.
Methodology
A systematic review was performed by searching PubMed, Cochrane Library, and Web of Science databases, resulting in the inclusion of seven studies after applying inclusion and exclusion criteria.
Potential Biases
The studies present an unclear risk of bias, with no clear descriptions of randomization or blinding.
Limitations
The evidence is limited as all studies were conducted on animals, and the technique has been used for less than 30 years.
Participant Demographics
The studies included 114 rats and mice, with ages ranging from 5 weeks to 8 months.
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website