Hepatic Dysfunction in Typhoid Fever During Pregnancy
Author Information
Author(s): Jorge Hasbun H., Raúl Osorio, André Hasbun
Primary Institution: University of Chile
Hypothesis
The study investigates the occurrence of hepatic dysfunction in pregnant women with typhoid fever.
Conclusion
Hepatic dysfunction was found in 31.2% of pregnant women with typhoid fever, leading to severe maternal and perinatal complications.
Supporting Evidence
- Hepatic dysfunction was observed in 10 out of 32 pregnant women with typhoid fever.
- Eight patients returned to normal after treatment and had successful pregnancies.
- Two cases were associated with severe maternal and perinatal complications.
Takeaway
Some pregnant women with typhoid fever can have liver problems, which can make them and their babies very sick.
Methodology
The study analyzed 32 pregnant women with typhoid fever treated at the University of Chile Clinical Hospital from 1978 to 1998.
Limitations
The study is limited by its retrospective nature and the small sample size.
Participant Demographics
Pregnant women with typhoid fever, primarily aged between 11 and 35 years.
Digital Object Identifier (DOI)
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