Two Alternating Motor Programs Drive Navigation in Drosophila Larva
2011

How Drosophila Larvae Navigate Temperature Changes

Sample size: 46 publication 10 minutes Evidence: moderate

Author Information

Author(s): Lahiri Subhaneil, Shen Konlin, Klein Mason, Tang Anji, Kane Elizabeth, Gershow Marc, Garrity Paul, Samuel Aravinthan D. T.

Primary Institution: Harvard University

Hypothesis

Drosophila larvae use two alternating motor programs to navigate temperature gradients.

Conclusion

Drosophila larvae navigate temperature gradients by alternating between peristalsis for forward movement and asymmetric contraction for head sweeping.

Supporting Evidence

  • Drosophila larvae navigate by alternating periods of forward movement and reorientation maneuvers.
  • Larvae exhibit cold-avoidance behavior by crawling towards warmer temperatures.
  • Turning decisions are influenced by the temperature gradient experienced by the larvae.

Takeaway

Drosophila larvae can move away from hot or cold areas by using two different ways to change direction while they crawl.

Methodology

The study used fluorescence microscopy to visualize muscle dynamics in transgenic Drosophila larvae as they navigated temperature gradients.

Potential Biases

The white mutation in transgenic larvae may affect neurotransmitter levels, potentially influencing behavior.

Limitations

The study focused only on second instar larvae and did not explore other developmental stages.

Participant Demographics

Second instar Drosophila larvae, both wild-type and transgenic.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1371/journal.pone.0023180

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