Genetic Counseling in Renal Masses
2008
Genetic Counseling in Renal Masses
publication
Evidence: moderate
Author Information
Author(s): José Antonio López-Guerrero, Zaida García-Casado, Antonio Fernández-Serra, José Rubio-Briones
Primary Institution: Fundación Instituto Valenciano de Oncología
Conclusion
Molecular genetic testing can improve diagnostic certainty and reduce unnecessary screening for at-risk family members of renal cancer patients.
Supporting Evidence
- Renal cell carcinoma affects approximately 150,000 people worldwide each year.
- Hereditary renal cell carcinoma syndromes are estimated to account for 1-4% of cases.
- Genetic testing can identify at-risk family members and improve early diagnosis.
Takeaway
This study talks about how genetic testing can help find out if family members are at risk for kidney cancer, which can help them get the right check-ups and treatments.
Methodology
The review focuses on the molecular bases of familial syndromes associated with small renal masses and the indications for familial studies in at-risk family members.
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website