Duhuo Jisheng Tang for Treating Knee Osteoarthritis
Author Information
Author(s): Lai Jung-Nien, Chen Huey-Jeng, Chen Chao-Chung, Lin Jer-Huei, Hwang Jing-Shiang, Wang Jung-Der
Primary Institution: National Yang-Ming University
Hypothesis
The study aims to evaluate the efficacy and safety of Duhuo Jisheng Tang (DJT) in reducing symptoms of degenerative osteoarthritis of the knee.
Conclusion
A 4-week therapy with DJT reduced pain and stiffness and improved physical functioning in patients with knee osteoarthritis.
Supporting Evidence
- Participants showed significant improvements in WOMAC scores for pain, stiffness, and physical functioning after two weeks.
- By week four, mean WOMAC scores for pain decreased from 22.2 to 16.1.
- 44 out of 68 patients reported no change in flaccidity symptoms after treatment.
Takeaway
This study tested a Chinese herbal medicine called DJT to see if it helps with knee pain. After taking it for four weeks, many people felt less pain and could move better.
Methodology
A prospective follow-up study with 68 osteoarthritis patients receiving DJT for four weeks, measuring outcomes using the WOMAC index and WHOQOL.
Potential Biases
Potential confounding factors such as placebo effect and natural symptom fluctuation.
Limitations
The study lacked a randomized placebo group and was observational in nature.
Participant Demographics
{"mean_age":59.2,"gender_distribution":{"male":37,"female":63},"education":{"junior_high_or_below":41,"university_or_above":34},"marital_status":{"married":82,"divorced_widowed_separated":15}}
Statistical Information
P-Value
p<0.001
Statistical Significance
p<0.001
Digital Object Identifier (DOI)
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