Decision-Model Estimation of the Age-Specific Disability Weight for Schistosomiasis Japonica: A Systematic Review of the Literature
2008

Estimating Disability from Schistosomiasis Japonica

publication Evidence: high

Author Information

Author(s): Charles H. King, Juerg Utzinger

Primary Institution: Case Western Reserve University School of Medicine

Hypothesis

How debilitating is schistosomiasis for an average person?

Conclusion

The study found that schistosomiasis japonica causes a significantly higher disability impact than previously estimated.

Supporting Evidence

  • The study found 9.8% disability for children and 18.6% for adults with schistosomiasis japonica.
  • These estimates are significantly higher than the previous 0.5%–0.6% disability weight assigned by the GBD program.
  • The findings align with recent assessments of chronic schistosomiasis japonica in China.

Takeaway

Schistosomiasis can make people very sick and tired, much more than we thought before.

Methodology

The study used a decision tree model to assess disease impact separately for children and adults based on existing literature.

Potential Biases

The original GBD program's assessments may have undervalued the impact of schistosomiasis due to reliance on non-expert panels.

Limitations

The analysis is limited to S. japonicum-related disease outcomes and has gaps in available data for certain infection-related outcomes.

Digital Object Identifier (DOI)

10.1371/journal.pntd.0000158

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication