How Palatal Rugae Develop in Mice
Author Information
Author(s): Pantalacci Sophie, Prochazka Jan, Martin Arnaud, Rothova Michaela, Lambert Anne, Bernard Laure, Charles Cyril, Viriot Laurent, Peterkova Renata, Laudet Vincent
Primary Institution: Institut de Génomique Fonctionnelle de Lyon
Hypothesis
The study investigates the sequential addition of palatal rugae and their role in palatal development.
Conclusion
Palatal rugae are added sequentially during palate growth, revealing a new developmental boundary influenced by activation-inhibition mechanisms.
Supporting Evidence
- Rugae develop in a specific order during palate growth.
- Activation-inhibition mechanisms are suggested to influence ruga positioning.
- Ruga 8 marks a significant boundary in palatal development.
Takeaway
Rugae are like little bumps in the mouth that grow in a specific order as the palate develops, helping scientists understand how our mouths form.
Methodology
The study used mouse embryos to track the development of palatal rugae through gene expression analysis and histological techniques.
Participant Demographics
Mouse embryos were used in the study.
Digital Object Identifier (DOI)
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