Synthesis, Characterisation and Antifungal Activities of Some New Copper(II) Complexes of Isomeric 3,5,7,7,10,12,14,14-Octamethyl-1,4,8,11-Tetraazacyclotetradecanes
1997

Antifungal Activities of New Copper(II) Complexes

publication Evidence: moderate

Author Information

Author(s): Saroj K.S. Hazari, Tapashi G. Roy, Benu K. Dey, Suvash C. Das, Edward R.T. Tiekink

Primary Institution: Department of Chemistry, University of Chittagong, Bangladesh

Hypothesis

The study investigates the antifungal activity of new copper(II) complexes formed with isomeric octamethyl tetraazacyclotetradecanes.

Conclusion

The antifungal activities of the isomeric ligands and their copper complexes were assessed, showing varying levels of effectiveness against different fungi.

Supporting Evidence

  • The antifungal activities were tested against three phytopathogenic fungi: Alternaria alternata, Curvalaria lunata, and Macrophomina phaseolina.
  • The activities of the ligands decreased upon coordination to copper(II).
  • Fungitoxicities were generally lower than those of related sulfur-containing Schiff bases.

Takeaway

The researchers made new copper compounds and tested them to see if they could stop certain fungi from growing.

Methodology

The antifungal activity was assessed using the poisoned food technique on potato dextrose agar with various copper complexes.

Limitations

The study does not specify the limitations encountered during the synthesis or testing of the complexes.

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