Primary PEComa of the bladder treated with primary excision and adjuvant interferon-alpha immunotherapy: a case report
2006
Case Report of Bladder PEComa Treated with Immunotherapy
Sample size: 1
publication
Evidence: moderate
Author Information
Author(s): Jeremy R Parfitt, Anthony J Bella, Bret M Wehrli, Jonathan I Izawa
Primary Institution: London Health Sciences Centre and University of Western Ontario
Conclusion
The case demonstrates that adjuvant therapies, including immunotherapy, may be effective for patients with locally advanced or metastatic genitourinary PEComa.
Supporting Evidence
- The patient is clinically free of disease 48 months after surgery.
- Pathological examination confirmed the diagnosis of PEComa.
- Adjuvant interferon-α immunotherapy was initiated based on the tumor's vascular nature.
Takeaway
A man had a rare tumor in his bladder, and after surgery and treatment with a special medicine, he has been healthy for four years.
Methodology
The patient underwent laparotomy, partial cystectomy, and adjuvant interferon-α immunotherapy.
Limitations
The effect of interferon-α on PEComa morphology could not be documented due to the absence of residual tumor.
Participant Demographics
A 48-year-old man.
Digital Object Identifier (DOI)
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