Salivary Cortisol and Total Antioxidant Capacity (TAC) as Biomarkers of Stress in Dental Medicine Students—A Pilot Study
2024

Stress and Salivary Biomarkers in Dental Students

Sample size: 44 publication 10 minutes Evidence: moderate

Author Information

Author(s): Otilia Bolos, Vanessa Bolchis, Ramona Dumitrescu, Vlad Alexa Tiberiu, Berivan Laura Rebeca Buzatu, Anca Marcu, Catalin Marian, Paula Diana Ciordas, Daniela Jumanca, Atena Galuscan, Octavia Balean, Mario Pérez-Sayáns, Ionut Luchian, Radu Iliescu, Mihaela Moscalu

Primary Institution: University of Medicine and Pharmacy 'Victor Babes', Timisoara, Romania

Hypothesis

This study aims to explore the relationship between academic stress and salivary biochemical markers, specifically cortisol and total antioxidant capacity (TAC), in dental students.

Conclusion

The study found that academic stress negatively impacts TAC while causing a moderate increase in salivary cortisol levels.

Supporting Evidence

  • Stress negatively impacts educational performance and can lead to psychological issues.
  • Salivary TAC levels decreased significantly during high-stress periods.
  • Cortisol levels showed slight, non-significant variability under stress.

Takeaway

When dental students are stressed, their bodies produce less of a substance that helps fight damage, and their stress hormone levels change a little.

Methodology

This cross-sectional study involved collecting saliva samples from dental students during low-stress and high-stress periods to measure cortisol and TAC levels.

Potential Biases

Selection bias may have been introduced by including only volunteers from a specific educational background.

Limitations

The study had a small sample size and was conducted at a single center, which may limit the generalizability of the findings.

Participant Demographics

The participants included 23 females (48.9%) and 21 males (44.7%), with an average age of 24.51 years.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.3390/medicina60121972

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