Effect of Chicken Comb Extract on Knee Osteoarthritis Pain
Author Information
Author(s): Douglas S Kalman, Maria Heimer, Anita Valdeon, Howard Schwartz, Eric Sheldon
Primary Institution: Miami Research Associates
Hypothesis
Does dietary supplementation with a natural extract of chicken combs high in hyaluronic acid improve pain relief and quality of life in knee osteoarthritis patients?
Conclusion
The study found that daily supplementation with hyaluronic acid from chicken combs improved quality of life markers in adults with knee osteoarthritis.
Supporting Evidence
- Subjects in both groups showed significant improvements in WOMAC pain and quality of life scores.
- The active supplement group reported higher improvements in physical function and total symptoms compared to placebo.
- 75% of subjects in the active group perceived improvement in joint pain.
Takeaway
Taking a special chicken extract might help people with knee pain feel better and live better.
Methodology
A randomized double-blind placebo-controlled trial with 20 subjects aged 40 and over, comparing 80 mg/day of Hyal-Joint® to placebo for 8 weeks.
Potential Biases
Potential bias due to the small sample size and the exploratory nature of the pilot study.
Limitations
The small sample size and short duration of the study limit the generalizability of the findings.
Participant Demographics
20 subjects, 9 men and 11 women, mean age 56.3 years.
Statistical Information
P-Value
0.943
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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