Effects of repetitive transcranial magnetic stimulation on prefrontal cortical activation in children with attention deficit hyperactivity disorder: a functional near-infrared spectroscopy study
2024

Effects of rTMS on Brain Activation in Children with ADHD

Sample size: 35 publication 10 minutes Evidence: moderate

Author Information

Author(s): Wang Jing, Zou Zhuo, Huang Haoyu, Zhang Yangping, He Xuemei, Su Hang, Wang Wenjuan, Chen Yingjuan, Liu Yun

Primary Institution: Kunming Children's Hospital, Kunming Medical University, Kunming, Yunnan, China

Hypothesis

This study investigates the effects of repetitive transcranial magnetic stimulation (rTMS) on prefrontal cortical activation in children with attention deficit hyperactivity disorder (ADHD).

Conclusion

rTMS shows promise as a treatment for ADHD by modulating prefrontal cortical activation.

Supporting Evidence

  • Post-treatment, the treatment group showed a more pronounced decrease in SNAP-scale scores compared to the control group.
  • Both groups demonstrated enhanced resting-state functional connectivity in the prefrontal cortex after treatment.
  • The treatment group recorded higher mean HbO2 concentrations in prefrontal cortical regions during the Go/no-go task.

Takeaway

This study found that a special treatment called rTMS can help kids with ADHD by making their brains work better.

Methodology

The study involved 40 children with ADHD who were randomly assigned to a treatment group receiving rTMS and a control group receiving non-pharmacological interventions, with evaluations using SNAP-IV scale scores and fNIRS.

Limitations

The small sample size may limit the generalizability of the results, and the study's cross-sectional design does not allow for conclusions about long-term effects.

Participant Demographics

The treatment group consisted of 17 children (12 males, 5 females) with an average age of 8.45 years, while the control group had 18 children (11 males, 7 females) with an average age of 8.23 years.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.3389/fneur.2024.1503975

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