F18 fluorodeoxyglucose uptake in progressive transformation of germinal centres
2008
F18 FDG-PET/CT and Progressive Transformation of Germinal Centres
Sample size: 1
publication
Evidence: low
Author Information
Author(s): Bhavya Rehani, Y Dowdy, A Bharija, P Strohmeyer
Primary Institution: Department of Internal Medicine, Kettering Medical Center, Ohio, United States
Hypothesis
Can PTGC present as a false positive finding on FDG-PET/CT in lymphoma patients?
Conclusion
PTGC can appear as a false positive on FDG-PET/CT scans in patients with a history of Hodgkin's disease.
Supporting Evidence
- FDG-PET/CT is more accurate than FDG-PET and CT alone for lymphoma staging.
- PTGC can be present in lymph node biopsies of lymphoma patients.
- False positives on FDG-PET/CT can arise from various conditions including PTGC.
Takeaway
A man with a history of Hodgkin's disease had a PET scan that showed something suspicious, but it turned out to be a benign condition called PTGC.
Methodology
The patient underwent FDG-PET/CT scanning and a subsequent lymph node biopsy.
Limitations
The study is based on a single case report.
Participant Demographics
A 53-year-old man with a history of Hodgkin's disease.
Digital Object Identifier (DOI)
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