Association between skin diseases and severe bacterial infections in children: case-control study
2006

Skin Diseases and Severe Infections in Children

Sample size: 101 publication Evidence: moderate

Author Information

Author(s): Mohammedamin Robbert SA, van der Wouden Johannes C, Koning Sander, Willemsen Sten P, Bernsen Roos MD, Schellevis François G, van Suijlekom-Smit Lisette WA, Koes Bart W

Primary Institution: Erasmus MC-University Medical Center Rotterdam

Hypothesis

Children with sepsis or bacteraemia more often presented with skin diseases to the general practitioner than other children.

Conclusion

Children admitted for sepsis or bacteraemia consulted the GP more often for skin diseases than other children, but the differences are not clinically relevant.

Supporting Evidence

  • Children with sepsis or bacteraemia consulted the GP more often for skin diseases than controls.
  • The odds ratio for skin diseases was 3.4 in cases versus GP controls.
  • Only 5% of cases consulted the GP for skin diseases prior to admission.

Takeaway

Kids who get really sick from infections sometimes had skin problems before, but it's not a big enough deal for doctors to worry about too much.

Methodology

A case-control study using data from the second Dutch national survey of general practice and the National Medical Registration of all hospital admissions in the Netherlands.

Limitations

The probability of a GP consultation for skin disease was only 5% among cases, indicating limited opportunity for GPs to reduce sepsis risk.

Participant Demographics

Children aged 0–17 years, with a mix of genders and socio-economic backgrounds.

Statistical Information

P-Value

0.03

Confidence Interval

[1.1–10.8]

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1471-2296-7-52

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