Global Analysis of Proline-Rich Tandem Repeat Proteins Reveals Broad Phylogenetic Diversity in Plant Secretomes
2011

Diversity of Proline-Rich Proteins in Plants

Sample size: 36815 publication Evidence: high

Author Information

Author(s): Aaron M. Newman, James B. Cooper

Primary Institution: University of California, Santa Barbara

Hypothesis

The evolutionary diversity of proline-rich tandem repeat proteins (TRPs) in plant secretomes has not been thoroughly explored.

Conclusion

The study identifies 31 distinct classes of proline-rich TRPs, revealing significant phylogenetic diversity and previously unrecognized secretome signatures in plants.

Supporting Evidence

  • 31 distinct classes of proline-rich TRPs were identified.
  • Most proline-rich TRP classes have unexpectedly restricted evolutionary distributions.
  • Extensins evolved before plant vascularization.

Takeaway

Plants have many different types of proteins that help build their cell walls, and this study found a lot more variety in these proteins than we thought.

Methodology

A computational approach was used to analyze millions of plant secretome sequences to identify and classify proline-rich TRPs.

Limitations

The analysis may be limited by the phylogenetic sampling bias of currently available sequence data.

Digital Object Identifier (DOI)

10.1371/journal.pone.0023167

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