Infections in Kidney Transplant Recipients in the French Caribbean
Author Information
Author(s): Laurène Tardieu, Gary Doppelt, Muriel Nicolas, Violaine Emal, Pascal Blanchet, Samuel Markowicz, Valérie Galantine, Pierre-Marie Roger, Joëlle Claudéon, Loïc Epelboin, Biagio Pinchera
Primary Institution: University Hospital of Guadeloupe
Hypothesis
What is the incidence of bacterial, fungal, and parasitic infections in kidney transplant recipients in the French Caribbean?
Conclusion
The study found a high incidence of infections among kidney transplant recipients in the French Caribbean, particularly bacterial infections.
Supporting Evidence
- 63% of patients developed an infection during follow-up.
- Bacterial infections were the most common, accounting for 84% of cases.
- Diabetes at the time of transplantation was significantly associated with a higher risk of infection.
- The study identified a higher incidence of tropical infections like nocardiosis and phaeohyphomycosis.
- UTIs were the most frequent infections, accounting for 53% of all cases.
- Mortality rate during follow-up was 12%, with 62.5% of deaths attributable to infection.
Takeaway
This study looked at kidney transplant patients in the Caribbean and found that many of them got infections, especially from bacteria.
Methodology
A multicenter retrospective cohort study was conducted including patients who received kidney transplants between January 2014 and October 2016.
Potential Biases
Potential biases due to missing data and the retrospective nature of the study.
Limitations
The study had a retrospective design, which led to some missing data, and the relatively small cohort size limits generalizability.
Participant Demographics
The median age of participants was 52 years, with a male-to-female ratio of 2:1.
Statistical Information
P-Value
p<0.05
Confidence Interval
[1.40–13.37], [1.59–36.81]
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website