In vivo observation of gold nanoparticles in the central nervous system of Blaberus discoidalis
2011

Studying Gold Nanoparticles in Cockroach Brains

Sample size: 18 publication Evidence: moderate

Author Information

Author(s): Rocha Aracely, Zhou Yan, Kundu Subrata, González Jorge M, Vinson S Bradleigh, Liang Hong

Primary Institution: Texas A&M University

Hypothesis

Can negatively charged gold nanoparticles interact with the central nervous system of Blaberus discoidalis?

Conclusion

The study found that gold nanoparticles affected the locomotion of cockroaches but did not significantly impact their life expectancy over two months.

Supporting Evidence

  • The negatively charged gold nanoparticles were successfully injected into the cockroach's central nervous system.
  • Cockroaches treated with nanoparticles showed increased activity for 17 days post-treatment.
  • After two months, the survival rate was 67% for treated cockroaches and 78% for control cockroaches.

Takeaway

Researchers injected tiny gold particles into cockroaches to see how they affect their movement and found that the particles changed how the roaches moved but didn't really hurt them.

Methodology

The study involved injecting negatively charged gold nanoparticles into the cockroach's central nervous system and observing their effects on locomotion and behavior over two months.

Limitations

The study only observed the cockroaches for two months, which may not be sufficient to assess long-term effects of the nanoparticles.

Participant Demographics

Male Blaberus discoidalis cockroaches, approximately 2.1 grams in weight.

Digital Object Identifier (DOI)

10.1186/1477-3155-9-5

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