Clostridium difficile Infection and Inflammatory Bowel Disease: A Review
2011
Clostridium difficile Infection and Inflammatory Bowel Disease: A Review
publication
Evidence: moderate
Author Information
Author(s): Preetika Sinh, Terrence A. Barrett, Laura Yun
Primary Institution: Feinberg School of Medicine, Northwestern University
Conclusion
Clostridium difficile infection (CDI) significantly worsens outcomes in patients with inflammatory bowel disease (IBD), leading to higher hospitalization rates and mortality.
Supporting Evidence
- Patients with inflammatory bowel disease (IBD) have a higher prevalence of CDI and worse outcomes.
- CDI leads to higher rates of hospitalization, surgery, and mortality in IBD patients compared to non-IBD patients.
- The emergence of a hypervirulent strain of C. difficile has contributed to increased CDI cases.
Takeaway
Clostridium difficile can make people with certain gut diseases very sick, and doctors need to check for it if they get worse.
Limitations
The review does not provide new data but summarizes existing literature, which may have variability in study designs and outcomes.
Digital Object Identifier (DOI)
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