Autoimmune Neuromuscular Disorders
2011

Autoimmune Neuromuscular Disorders

publication Evidence: moderate

Author Information

Author(s): Jessica Kraker, Saša A Živković

Primary Institution: University of Pittsburgh Medical Center

Conclusion

Autoimmune neuromuscular disorders have diverse mechanisms and treatment options, but many treatments are based on corticosteroids and immunoglobulins.

Supporting Evidence

  • Autoimmune neuromuscular disorders can affect peripheral nerves, neuromuscular junctions, or muscles.
  • Treatment protocols often include corticosteroids, intravenous immunoglobulins, and plasmapheresis.
  • New monoclonal antibody treatments target specific immune pathways but may have unknown long-term effects.

Takeaway

Some people have problems with their nerves and muscles because their immune system attacks them. Doctors use different medicines to help these people feel better.

Limitations

The long-term efficacy of newer treatments is still unknown, and many treatments have associated adverse effects.

Digital Object Identifier (DOI)

10.2174/157015911796558000

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