Endometriosis and IVF Outcomes
Author Information
Author(s): Spandorfer SD, C Fierro, Kligman, H-C Liu, A Neuer, SS Witkin, Z Rosenwaks
Primary Institution: The Center for Reproductive Medicine and Infertility, Department of Obstetrics and Gynecology, The New York Hospital--Cornell Medical Center, New York, NY.
Hypothesis
The presence and stage of endometriosis affect the outcomes of in vitro fertilization with embryo transfer (IVF-ET).
Conclusion
The stage of endometriosis does not significantly affect pregnancy outcomes in IVF-ET, and the presence of endometriosis alone does not impact these outcomes.
Supporting Evidence
- 84.4% of cycles initiated went to retrieval.
- 92.3% of retrievals underwent embryo transfer.
- Clinical pregnancy rate per transfer was 44.7%.
- Age significantly affected IVF-ET outcomes, with younger patients having higher success rates.
Takeaway
This study looked at how endometriosis affects pregnancy success with IVF. It found that having endometriosis doesn't really change the chances of getting pregnant through IVF.
Methodology
Retrospective analysis of 1417 IVF-ET cycles in patients with endometriosis from 1989 to 1997.
Limitations
The study is retrospective and may not account for all variables affecting IVF outcomes.
Participant Demographics
Patients undergoing IVF-ET with varying stages of endometriosis.
Statistical Information
P-Value
p<0.001
Statistical Significance
p<0.05
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