Prognostic Value of DNA Flow Cytometry in Stomach Cancer
Author Information
Author(s): Lee K H, Lee J S, Lee J H, Kim S W, Suh C, Kim W K, Kim S-H, Min Y I, Kim B S, Park K C, Lee M S, Sun H S
Primary Institution: University of Ulsan, College of Medicine, Asan Medical Center
Hypothesis
The study investigates the role of DNA flow cytometry as a prognostic indicator in stomach cancer patients.
Conclusion
DNA flow cytometry can independently predict survival in stomach cancer patients based on the S-phase fraction of tumors.
Supporting Evidence
- Aneuploid cell population was found in 53% of samples.
- Patients with S-phase fraction over 17% had worse survival rates.
- The TNM stage was the most important prognostic indicator.
Takeaway
Doctors can use a test called DNA flow cytometry to help predict how well patients with stomach cancer will do based on certain tumor characteristics.
Methodology
The study involved DNA flow cytometric analyses of tumor samples from 217 stomach cancer patients, correlating results with patient survival.
Participant Demographics
Median age of patients was 55 years, with 148 males and 69 females.
Statistical Information
P-Value
0.007
Confidence Interval
1.252–4.223
Statistical Significance
p=0.007
Digital Object Identifier (DOI)
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