Factors affecting aseptic loosening of 4750 total hip arthroplasties: multivariate survival analysis
2007

Factors Affecting Aseptic Loosening in Total Hip Arthroplasties

Sample size: 4750 publication 10 minutes Evidence: moderate

Author Information

Author(s): Bordini Barbara, Stea Susanna, De Clerico Manuela, Strazzari Sergio, Sasdelli Antonio, Toni Aldo

Primary Institution: Istituti Ortopedici Rizzoli

Hypothesis

What are the risk factors that influence aseptic failure in total hip arthroplasties?

Conclusion

The type of prosthesis significantly affects survival, with lower-cost options associated with a higher risk of failure.

Supporting Evidence

  • Male patients under 40 years old have a higher risk of prosthesis failure.
  • Cemented prostheses are associated with a higher risk of failure compared to uncemented ones.
  • Surgeons with less experience (fewer than 400 operations) have higher failure rates.
  • Certain diseases increase the risk of prosthesis failure.

Takeaway

This study found that some types of hip implants are more likely to fail than others, especially cheaper ones.

Methodology

Multivariate survival analysis was applied to 4,750 primary total hip arthroplasties performed between 1995 and 2000.

Potential Biases

The study may be influenced by the experience of the surgeons and the specific characteristics of the hospital.

Limitations

The low revision rate (less than 3%) limits the analysis of primary total hip arthroplasty outcomes.

Participant Demographics

Patients included 4,450 individuals with varying ages, genders, and diagnoses.

Statistical Information

P-Value

p = 0.001

Confidence Interval

95% CI

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1471-2474-8-69

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