First detection and characterization of genetically divergent canine calicivirus strains in domestic dogs in China
2024

First Detection of Canine Calicivirus in Dogs in China

Sample size: 52 publication Evidence: moderate

Author Information

Author(s): Li Sihan, Chu Liangyu, Zhang Yancheng, Yu Yaxuan, Wang Guoqing

Primary Institution: Northeastern University, Shengyang, China

Hypothesis

What are the genetic characteristics of canine calicivirus (CaCV) in domestic dogs in China?

Conclusion

This study identified two genetically divergent strains of canine calicivirus in dogs in China.

Supporting Evidence

  • Two strains of canine calicivirus were identified from 52 samples.
  • The complete genome sequences of the strains were obtained and analyzed.
  • The strains showed 83.6% nucleotide similarity with each other.
  • The strains had 71.6%−90.2% similarity with previously reported CaCV strains.
  • Phylogenetic analysis indicated that the strains belonged to different evolutionary branches.

Takeaway

Researchers found a new virus in dogs in China that is different from other known viruses. They studied its genes to understand how it might affect dogs.

Methodology

The study collected 52 nasal swab samples from dogs and tested them for CaCV using RT-PCR.

Limitations

The study did not include anal swab testing, which may affect the detection rate of the virus.

Participant Demographics

Dogs from Liaoning Province, China.

Digital Object Identifier (DOI)

10.3389/fvets.2024.1501632

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