Results from a seven-year programme of breast self-examination in 89,010 women
1989

Breast Self-Examination Study Results

Sample size: 89010 publication 10 minutes Evidence: moderate

Author Information

Author(s): A.P. Locker, J. Caseldine, A.K. Mitchell, R.W. Blamey, E.J. Roebuck, C.W. Elston

Primary Institution: Nottingham General Hospital and City Hospital, Nottingham, UK

Hypothesis

Does breast self-examination (BSE) improve survival rates in women?

Conclusion

The study found that while BSE did not show an overall survival advantage, women who attended BSE education had better survival rates and presented with smaller, less aggressive tumors.

Supporting Evidence

  • Women who attended BSE education had a significantly better survival rate at 13 years.
  • Patients who practiced BSE presented with smaller tumors and more favorable histological grades.
  • The study population had a higher proportion of grade I tumors compared to historical controls.
  • Attendance for BSE education was associated with a relative risk of dying from breast cancer of 0.66 in post-menopausal women.

Takeaway

Teaching women how to check their breasts can help them find cancer earlier, which is better for their health.

Methodology

The study compared outcomes between women educated in BSE and historical controls, analyzing tumor characteristics and survival rates.

Potential Biases

Potential bias due to the non-randomized nature of the study and reliance on historical controls.

Limitations

The study was not a randomized controlled trial and relied on historical controls, which may introduce bias.

Participant Demographics

Women aged 40-65 in Nottingham, UK.

Statistical Information

P-Value

p<0.001

Statistical Significance

p<0.001

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