Link Between Premenstrual Disorders and Perinatal Depression
Author Information
Author(s): Ohsuga Takuma, Egawa Miho, Tsuyuki Kaori, Ueda Akihiko, Komatsu Maya, Chigusa Yoshitsugu, Mogami Haruta, Mandai Masaki
Primary Institution: Kyoto University Graduate School of Medicine
Hypothesis
Is there an association between preconception premenstrual disorders and perinatal depression?
Conclusion
Premenstrual disorders are a significant risk factor for depression during pregnancy and postpartum.
Supporting Evidence
- Women with preconception PMDs had a higher likelihood of scoring above the depression threshold during pregnancy.
- 34.0% of women with preconception PMDs scored above the postpartum depression threshold at one month postpartum.
- The study used a comprehensive perinatal clinical database to analyze the data.
- Logistic regression analyses adjusted for various factors confirmed the association between PMDs and perinatal depression.
Takeaway
Women who have problems with their periods before getting pregnant are more likely to feel sad during and after their pregnancy.
Methodology
Data from pregnant women who gave birth at Kyoto University Hospital were analyzed using logistic regression to assess the association between preconception PMDs and perinatal depression.
Potential Biases
Recall bias may have influenced the results due to reliance on participants' memory of premenstrual symptoms.
Limitations
The study relied on self-reported data, which may be subject to recall bias, and the findings may not be generalizable beyond a single institution.
Participant Demographics
The study included 781 pregnant women, with 53 having preconception PMDs.
Statistical Information
P-Value
5.78 (crude OR), 3.71 (adjusted OR)
Confidence Interval
95% CI: 2.70–11.75 (crude), 95% CI: 1.54–8.35 (adjusted)
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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