Vaccinia Virus Infection in Monkeys, Brazilian Amazon
2010

Vaccinia Virus Infection in Monkeys in Brazil

Sample size: 344 publication Evidence: moderate

Author Information

Author(s): Abrahão Jônatas S., Silva-Fernandes André T., Lima Larissa S., Campos Rafael K., Guedes Maria I.M.C., Cota Marcela M.G., Assis Felipe L., Borges Iara A., Souza-Júnior Milton F., Lobato Zélia I.P., Bonjardim Cláudio A., Ferreira Paulo C.P., Trindade Giliane S., G. Erna

Primary Institution: Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil

Hypothesis

To detect orthopoxvirus in the Brazilian Amazon, we conducted a serosurvey of wild animals.

Conclusion

The study found a high prevalence of orthopoxvirus antibodies among capuchin and black-howling monkeys in the Brazilian Amazon.

Supporting Evidence

  • Neutralizing antibodies against orthopoxvirus were detected in 84 serum samples.
  • 68 out of 269 capuchin monkeys tested positive for orthopoxvirus antibodies.
  • 13 out of 27 black-howling monkeys tested positive for orthopoxvirus antibodies.
  • 18 of 344 serum samples were positive in PCR assays.

Takeaway

Scientists checked wild animals in Brazil to see if they had a virus called vaccinia, and they found that many monkeys were infected.

Methodology

A serosurvey was conducted where 344 wild mammals were captured, and serum samples were tested for orthopoxvirus antibodies using plaque-reduction neutralization tests.

Limitations

Clinical data for pox lesions in animals tested were not well documented.

Participant Demographics

The study included various wild mammal species, primarily capuchin and black-howling monkeys.

Digital Object Identifier (DOI)

10.3201/eid1606.091187

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