Association between serum levels of C-reactive protein and personality traits in women
2008

C-reactive protein and personality traits in women

Sample size: 270 publication 10 minutes Evidence: moderate

Author Information

Author(s): Henningsson Susanne, Baghaei Fariba, Rosmond Roland, Holm Göran, Landén Mikael, Anckarsäter Henrik, Ekman Agneta

Primary Institution: Göteborg University

Hypothesis

Is there an association between serum levels of C-reactive protein (CRP) and personality traits in women?

Conclusion

Serum levels of CRP in women were found to be associated with the personality traits harm avoidance and self-directedness.

Supporting Evidence

  • Harm avoidance was positively associated with CRP levels.
  • Self-directedness was negatively associated with CRP levels.
  • Women with ongoing depression had higher CRP levels than non-depressed women.

Takeaway

This study found that women who are more anxious and less self-directed have higher levels of a protein that indicates inflammation in the body.

Methodology

Serum levels of high-sensitivity CRP were determined by ELISA in 270 women assessed using the Temperament and Character Inventory.

Potential Biases

Participants who volunteered may not represent the general population.

Limitations

The study had a relatively small sample size and relied on self-reported measures of depression.

Participant Demographics

The study included 270 women, all aged 42, from Göteborg, Sweden.

Statistical Information

P-Value

p < 0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1744-9081-4-16

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