Exocrine Pancreatic Insufficiency in Diabetes Mellitus
Author Information
Author(s): Philip D. Hardt, Nils Ewald
Primary Institution: University Hospital Giessen and Marburg
Hypothesis
Is exocrine pancreatic insufficiency a complication of diabetic neuropathy or a different type of diabetes?
Conclusion
Exocrine pancreatic insufficiency is common in diabetes mellitus and may be linked to diabetic neuropathy.
Supporting Evidence
- Exocrine pancreatic insufficiency is found in about 50% of patients with type 1 diabetes.
- Changes in pancreatic morphology are frequently observed in diabetic patients.
- Diabetic neuropathy may contribute to exocrine pancreatic insufficiency.
Takeaway
People with diabetes can have problems with their pancreas that make it hard for them to digest food properly, which can cause stomach issues.
Methodology
A Medline search was performed to review literature on diabetes mellitus and exocrine pancreatic insufficiency.
Potential Biases
Potential bias due to the selective nature of studies included in the review.
Limitations
Many studies had small sample sizes and were limited by invasive testing methods.
Participant Demographics
Patients with type 1 and type 2 diabetes mellitus.
Statistical Information
P-Value
0.004
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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