Antimicrobial and Antibiofilm Activity of Origanum vulgare Extracts Obtained by Supercritical Fluid Extraction Under Various Extraction Conditions
2024

Antimicrobial and Antibiofilm Activity of Oregano Extracts

publication 10 minutes Evidence: moderate

Author Information

Author(s): Gwiazdowska Daniela, Waśkiewicz Agnieszka, Juś Krzysztof, Marchwińska Katarzyna, Frąk Szymon, Popowski Dominik, Pawlak-Lemańska Katarzyna, Uwineza Pascaline Aimee, Gwiazdowski Romuald, Padewska Daria, Roszko Marek, Bryła Marcin

Primary Institution: Poznań University of Economics and Business

Hypothesis

This study aims to determine the biological activity of extracts obtained from Origanum vulgare L. by supercritical CO2 extraction using different reaction conditions and compositions.

Conclusion

Oregano extracts obtained by supercritical CO2 extraction show significant antimicrobial and antibiofilm activity against various bacteria and fungi.

Supporting Evidence

  • The extracts showed antimicrobial activity against bacteria like Salmonella and Listeria.
  • Fluorescence microscopy revealed changes in fungal cell viability and morphology.
  • Antibiofilm properties were stronger against Gram-positive bacteria.
  • Phytochemical analysis identified several bioactive compounds in the extracts.

Takeaway

Oregano extracts can help fight germs and prevent biofilms, which are like sticky layers of bacteria, making them useful for food safety.

Methodology

The study used supercritical CO2 extraction to obtain oregano extracts and tested their antimicrobial and antibiofilm properties against various microorganisms.

Limitations

The study's results may vary based on extraction conditions and the specific microorganisms tested.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.3390/molecules29245823

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