Five-Year Trends in Low-Density Lipoprotein Cholesterol Management in a Primary Healthcare Centre in Kaunas
2024

Trends in Managing Cholesterol Levels in Patients

Sample size: 18646 publication 10 minutes Evidence: moderate

Author Information

Author(s): Urbonas Gediminas, Šileikienė Lolita, Valius Leonas, Grigalė Evelina, Kaupas Vilius, Juška Tautvydas, Vėbraitė Gabrielė, Grabauskytė Ingrida

Primary Institution: Lithuanian University of Health Sciences

Hypothesis

This study evaluated LDL-C control trends in patients treated at a primary healthcare center in Lithuania.

Conclusion

LDL-C control trends are improving over five years, but many patients still do not meet target levels.

Supporting Evidence

  • LDL-C levels decreased significantly in patients with diabetes and CVD compared to the control group.
  • The proportion of patients achieving LDL-C < 3 mmol/L increased from 32.0% in 2019 to 41.5% in 2023.
  • Patients with diabetes saw a 3.5-fold increase in achieving LDL-C < 1.8 mmol/L over five years.
  • Patients with CVD had a 4.7-fold increase in achieving LDL-C < 1.4 mmol/L.
  • Positive trends in LDL-C control suggest potential long-term reductions in cardiovascular events.

Takeaway

Doctors are getting better at helping patients lower their bad cholesterol, but many still need help to reach healthy levels.

Methodology

Data on patients aged 40 years or older diagnosed with dyslipidemia were extracted from a real-world data platform over five years.

Potential Biases

Potential misclassification of patients in the control group could affect results.

Limitations

The study was conducted at a single center, limiting generalizability, and the control group may include some high-risk patients.

Participant Demographics

The study included 58.2% women, with a mean age of 58.1 years.

Statistical Information

P-Value

p<0.001

Confidence Interval

95% CI

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.3390/medicina60121963

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