Secular trends in cholesterol lipoproteins and triglycerides and prevalence of dyslipidemias in an urban Indian population
2008

Trends in Cholesterol and Triglycerides in Urban India

Sample size: 4136 publication 10 minutes Evidence: moderate

Author Information

Author(s): Rajeev Gupta, Soneil Guptha, Aachu Agrawal, Vijay Kaul, Kiran Gaur, Vijay P. Gupta

Primary Institution: Fortis Escorts Hospital, Jaipur, India

Hypothesis

To determine secular trends in prevalence of various lipid abnormalities in an urban Indian population.

Conclusion

The study found an increase in mean total, non-HDL, remnant, and total:HDL cholesterol levels, as well as triglycerides, while HDL cholesterol levels declined.

Supporting Evidence

  • Mean cholesterol levels increased significantly from 1993 to 2005.
  • Prevalence of high non-HDL cholesterol and triglycerides increased over the years.
  • Educational level correlated with increasing obesity and dyslipidemias.

Takeaway

This study shows that more people in urban India have high cholesterol and triglycerides now than before, which can lead to heart problems.

Methodology

The study used successive epidemiological studies (Jaipur Heart Watch) to evaluate adults for coronary risk factors and measured cholesterol and triglyceride levels.

Potential Biases

Potential biases from compiling studies with different methodologies.

Limitations

Variable and low response rates in some cohorts may affect data reliability.

Participant Demographics

Adults aged 20-59 years, with 2341 men and 1795 women included.

Statistical Information

P-Value

p<0.001

Confidence Interval

95% CI for various parameters reported

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.1186/1476-511X-7-40

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication