Mitral Annulus Calcification is associated with valvular and cardiac structural abnormalities

2007

Mitral Annulus Calcification and Heart Problems

Sample size: 24380 publication Evidence: high

Author Information

Author(s): Movahed Mohammad-Reza, Saito Yuji, Ahmadi-Kashani Mastaneh, Ebrahimi Ramin

Primary Institution: University of Arizona Sarver Heart Center

Is mitral annulus calcification associated with cardiac abnormalities?

Mitral annulus calcification is linked to significant structural heart abnormalities.

MAC was reported in 1,494 (6.1%) subjects.
Age, LVH, MR, TR, AS, LA enlargement, and reversed E/A ratio were independently associated with MAC.
MAC was noted in 11.7% of patients with MR vs. 4.3% without MR.
MAC was noted in 13.9% of those with TR vs. 4.5% without TR.
MAC was noted in 10.6% with LVH vs. 4.2% without LVH.
MAC was noted in 14.8% with AS vs. 5.5% without AS.
MAC was noted in 9.4% with reversed E/A ratio vs. 3.8% without reversed E/A ratio.
MAC was noted in 8.2% with LA enlargement vs. 4.8% without LA enlargement.

When doctors find calcium buildup in a heart valve, it might mean there are other heart problems too.

Retrospective review of 24,380 echocardiograms from 1984 to 1998.

The diagnoses of cardiac abnormalities were not standardized.

The study relied on previous reports, leading to non-uniform assessment of echocardiographic abnormalities.

Mean age of patients with MAC was 68 years.

< 0.0001

1.6–2.6

p<0.0001

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