Vein of Galen Aneurysmal Malformations: Updates on Technical Aspects and Functional Outcomes Post-Endovascular Treatment—A Systematic Review and Meta-Analysis
2024

Updates on Vein of Galen Aneurysmal Malformations Treatment

Sample size: 400 publication Evidence: moderate

Author Information

Author(s): Talía Fuentes-Redondo, Pedro Navia-Álvarez, Luis-Alfonso Arráez-Aybar, Mihaela Hostiuc

Primary Institution: Complejo Hospitalario de Toledo, La Paz University Hospital, Complutense University of Madrid

Hypothesis

The study aims to update the anatomical and technical aspects of managing vein of Galen aneurysmal malformations (VGAMs) after endovascular treatment.

Conclusion

The angioarchitecture of VGAMs significantly influences treatment planning and functional outcomes.

Supporting Evidence

  • 400 cases of VGAMs were evaluated.
  • 84.8% of patients underwent endovascular treatment.
  • Complete occlusion was achieved in 62.3% of patients.
  • Functional outcome was classified as good in 68% of surviving patients.
  • The average follow-up time was 43.18 months.

Takeaway

This study looks at how doctors treat a rare brain problem in babies called vein of Galen malformations, and it finds that understanding the blood vessels involved helps doctors do a better job.

Methodology

A systematic review of original articles published between 1 January 2014 and 1 February 2024 was conducted, following PRISMA guidelines.

Potential Biases

High risk of bias due to retrospective designs and selection bias.

Limitations

The main limitations include retrospective study designs, small sample sizes, and potential biases in the included studies.

Participant Demographics

65.1% male, with ages ranging from prenatal to adults, and most cases diagnosed in neonates and infants.

Digital Object Identifier (DOI)

10.3390/medicina60121948

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