Olmesartan-Induced Enteropathy: A Rare Case of Chronic Diarrhea
2024

Olmesartan-Induced Enteropathy: A Rare Case of Chronic Diarrhea

Sample size: 1 publication Evidence: low

Author Information

Author(s): Gurgel Sofia Emerenciano, de Medeiros Kleyton Santos, Lima de Paiva Sarah Jane, Gurgel Filho José

Primary Institution: University of Pittsburgh, Pittsburgh, Pennsylvania, USA

Hypothesis

Can olmesartan cause chronic diarrhea in patients?

Conclusion

The patient's diarrhea improved rapidly after discontinuing olmesartan, confirming it as the cause of his enteropathy.

Supporting Evidence

  • The patient experienced significant improvement after stopping olmesartan.
  • Histological findings confirmed the diagnosis of olmesartan-induced enteropathy.
  • The patient regained weight and normalized his duodenal histology after treatment.

Takeaway

A man had severe diarrhea because of a blood pressure medicine called olmesartan, but he got better after stopping the medicine.

Methodology

The case involved a detailed clinical examination, laboratory tests, and biopsies to diagnose olmesartan-induced enteropathy.

Potential Biases

Potential bias in diagnosis due to the complexity of symptoms and previous treatments.

Limitations

The case report is based on a single patient, limiting the generalizability of the findings.

Participant Demographics

A 63-year-old hypertensive man.

Digital Object Identifier (DOI)

10.1155/carm/2666671

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