Levels of PBDEs and PCBs in Japanese Mothers' Serum and Breast Milk
Author Information
Author(s): Inoue Kayoko, Harada Kouji, Takenaka Katsunobu, Uehara Shigeki, Kono Makoto, Shimizu Takashi, Takasuga Takumi, Senthilkumar Kurunthachalam, Yamashita Fumiyoshi, Koizumi Akio
Primary Institution: Kyoto University Graduate School of Medicine
Hypothesis
What are the current levels of PBDEs and PCBs in Japanese women, and how do lifestyle and dietary habits affect these levels?
Conclusion
BDE-209 was the most abundant PBDE in serum but was less prevalent in milk, with geographic location and nursing duration being key factors affecting contaminant levels.
Supporting Evidence
- BDE-209 was the most predominant PBDE congener in serum but not in milk.
- The geometric means of total PBDE concentrations were 1.56 ng/g in milk and 2.89 ng/g in serum.
- Geographic area was a major determinant of total PBDE concentration in serum and milk.
- Nursing duration significantly affected PCB concentration levels.
Takeaway
This study looked at how much of certain chemicals are in the blood and milk of Japanese mothers, finding that where they live and how long they breastfeed affects these levels.
Methodology
Blood and breast milk samples were collected from mothers in four regions of Japan, and levels of PBDEs and PCBs were measured using high-resolution gas chromatography and mass spectrometry.
Limitations
The study may not account for all potential sources of exposure to PBDEs and PCBs.
Participant Demographics
Participants were lactating mothers aged 20 to 43 years from four regions in Japan.
Statistical Information
P-Value
p<0.01
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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