Association between oxidative balance score and serum cobalt level in population with metal implants: a cross-sectional study from NHANES 2015–2020
2024

Link Between Oxidative Balance and Cobalt Levels in People with Metal Implants

Sample size: 549 publication 10 minutes Evidence: moderate

Author Information

Author(s): Yuan Wenxiu, Chen Jing, Sun Jun, Song Chenyang, Chen Zhi

Primary Institution: Fujian Medical University

Hypothesis

What is the relationship between oxidative balance score and serum cobalt levels in individuals with metal implants?

Conclusion

The study found that higher oxidative balance scores are associated with lower serum cobalt levels in individuals with metal implants.

Supporting Evidence

  • The dietary oxidative balance score was negatively associated with serum cobalt levels.
  • Negative correlations were significant in males and participants aged over 70.
  • Maintaining a healthy lifestyle can help reduce metal ion toxicity.

Takeaway

Eating healthy foods and living a healthy lifestyle can help people with metal implants have lower levels of cobalt in their blood, which is better for their health.

Methodology

A cross-sectional study using NHANES data from 2015 to 2020, analyzing dietary and lifestyle factors to calculate oxidative balance scores and their relationship with serum cobalt levels.

Potential Biases

Recall and reporting biases may affect the accuracy of oxidative balance score calculations.

Limitations

The study's cross-sectional design limits causal inferences, and there were issues with missing data and potential biases in self-reported questionnaires.

Participant Demographics

Participants included individuals with metal implants, with subgroup analyses by age and gender.

Statistical Information

P-Value

0.04918

Confidence Interval

95%CI: −0.358 to −0.001

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.3389/fnut.2024.1485428

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