Range of Flexion Improvement in Degenerative Stages of the First Metatarsophalangeal Joint (Hallux rigidus) with Cross-Linked Hyaluronic Acid: A Cadaveric Study
2024

Improving Joint Movement in Hallux Rigidus with Hyaluronic Acid

Sample size: 10 publication 10 minutes Evidence: moderate

Author Information

Author(s): Capell Morera Annabel, de Planell Mas Elena, Pérez Palma Laura, Manzanares-Céspedes Maria Cristina

Primary Institution: University of Barcelona

Hypothesis

Does a single dose of cross-linked hyaluronic acid improve the range of mobility of the first metatarsophalangeal joint?

Conclusion

The study found that injecting cross-linked hyaluronic acid significantly improved the range of motion in the first metatarsophalangeal joint without causing damage to surrounding structures.

Supporting Evidence

  • The study showed a significant increase in loaded dorsiflexion from 47° to 58°.
  • Unloaded dorsiflexion also improved from 41° to 58° after treatment.
  • No injuries to anatomical structures were observed during the study.

Takeaway

This study shows that a special gel can help a stiff toe move better without hurting the surrounding parts.

Methodology

Ten fresh frozen feet were injected with cross-linked hyaluronic acid, and their range of motion was measured before and after the procedure.

Potential Biases

Potential bias in sample selection and the off-label use of the product.

Limitations

The study used cadaveric specimens, which may not fully represent living patients.

Participant Demographics

4 men and 6 women, average age 87.5 years.

Statistical Information

P-Value

0.006 for loaded dorsiflexion, 0.009 for unloaded dorsiflexion, 0.083 for unloaded plantarflexion

Confidence Interval

[37; 51.5] for loaded dorsiflexion, [40; 51.5] for unloaded dorsiflexion, [10.5; 24.25] for unloaded plantarflexion

Statistical Significance

p<0.01

Digital Object Identifier (DOI)

10.3390/jfmk9040259

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