A case control study of premorbid and currently reported physical activity levels in chronic fatigue syndrome
2006

Activity Levels in Chronic Fatigue Syndrome Patients

Sample size: 66 publication Evidence: moderate

Author Information

Author(s): Wayne R. Smith, Peter D. White, Dedra Buchwald

Primary Institution: University of Washington

Hypothesis

Do patients with chronic, unexplained, disabling fatigue perceive their premorbid activity levels as higher than the current activity levels perceived by healthy matched controls?

Conclusion

Patients with chronic, unexplained, disabling fatigue reported being more active before becoming ill than healthy controls.

Supporting Evidence

  • Patients rated themselves as more active before their illness compared to healthy controls.
  • Patients reported less current activity than healthy controls.
  • The differences in activity levels remained significant for patients meeting strict criteria for chronic fatigue syndrome or fibromyalgia.

Takeaway

People who feel very tired all the time used to be more active before they got sick, but now they do less than healthy people.

Methodology

A case-control study comparing 33 patients with chronic fatigue to 33 healthy controls using self-reported activity levels.

Potential Biases

Self-reported measures may lead to overestimation of previous activity levels.

Limitations

The sample may not be generalizable to all patients with chronic fatigue, and the measures were self-reported and not validated against objective measures.

Participant Demographics

Patients were adults evaluated in a university-based clinic, with 79% female and a mean age of 45.6 years.

Statistical Information

P-Value

p ≤ 0.001

Statistical Significance

p ≤ 0.001

Digital Object Identifier (DOI)

10.1186/1471-244X-6-53

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