Mycobacterium mageritense Pulmonary Disease in Patient with Compromised Immune System
2011

Mycobacterium mageritense Pulmonary Disease in an Immunocompromised Patient

Sample size: 1 publication Evidence: low

Author Information

Author(s): Huth R. Gordon, Brown-Elliott Barbara A., Wallace Richard J. Jr.

Primary Institution: University of Texas Southwestern Residency Programs

Hypothesis

Can Mycobacterium mageritense cause pulmonary disease in immunocompromised patients?

Conclusion

The case demonstrates that Mycobacterium mageritense can cause pneumonia in patients with compromised immune systems.

Supporting Evidence

  • Mycobacterium mageritense was first described in 1997 and associated with disease in the U.S. in 2002.
  • The patient had a long history of autoimmune diseases and was on immunosuppressive therapy.
  • Multiple antimicrobial treatments were attempted without improvement until specific antibiotics were prescribed.

Takeaway

This study shows that a specific type of bacteria, Mycobacterium mageritense, can make sick people with weak immune systems, like those with autoimmune diseases.

Methodology

The case study involved clinical evaluation, imaging, and microbiological testing to identify the pathogen.

Limitations

The study is based on a single case, limiting generalizability.

Participant Demographics

The patient was a 54-year-old woman with multiple health issues including systemic lupus erythematosus.

Digital Object Identifier (DOI)

10.3201/eid1703.101279

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