Ecological Niche of the 2003 West Nile Virus Epidemic in the Northern Great Plains of the United States
2008

Ecological Niche of the 2003 West Nile Virus Epidemic

Sample size: 4490 publication Evidence: moderate

Author Information

Author(s): Michael C. Wimberly, Michael B. Hildreth, Stephen P. Boyte, Erik Lindquist, Lon Kightlinger

Primary Institution: South Dakota State University

Hypothesis

Spatial patterns of West Nile virus in the northern Great Plains are determined by environmental drivers.

Conclusion

The spatial pattern of West Nile virus cases during the 2003 epidemic was associated with climatic gradients and land use patterns.

Supporting Evidence

  • The incidence of West Nile virus was found to have a stronger relationship with long-term climate patterns than with annual weather.
  • A single large cluster of elevated West Nile virus risk was identified across multiple states.
  • The study indicated that environmental conditions create a favorable ecological niche for Culex tarsalis, a key vector of West Nile virus.

Takeaway

This study looked at why West Nile virus was so common in the northern Great Plains in 2003, finding that weather and land use helped mosquitoes spread the virus.

Methodology

County-level data on West Nile virus cases were analyzed using spatial cluster analysis and statistical models with weather, climate, and land use variables as predictors.

Potential Biases

Potential biases may arise from the spatial autocorrelation in the data.

Limitations

The analysis focused on a single epidemic year and at a coarse spatial resolution, which may overlook finer-scale environmental relationships.

Participant Demographics

The study area included counties in North Dakota, South Dakota, Nebraska, eastern Montana, and Wyoming.

Statistical Information

P-Value

p<0.05

Confidence Interval

7.3 (5.8–9.1) in 2002, 24.2 (22.4–26.1) in 2003

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1371/journal.pone.0003744

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