Quantitative assessment of global and regional strain in relation to infarct size in patients with myocardial infarction
2011

Assessing Heart Function After Heart Attacks

Sample size: 80 publication Evidence: moderate

Author Information

Author(s): Shafi Nabil A, Bertman Kathleen, Yoon Andrew, Toole Rena, Ronin Matthew, Pollack Simcha, Reichek Nathaniel, Kadiyala Madhavi

Primary Institution: St. Francis Hospital- The Heart Center, Roslyn, NY, USA

Hypothesis

The study aims to characterize left ventricular global and regional strains in patients with prior myocardial infarction using FT-MRI and determine the relationship of strains to infarct size, location, and LV ejection fraction.

Conclusion

FT-MRI allows for detailed assessment of heart function in patients with heart attacks, showing decreased global strain and preserved longitudinal strain in most cases.

Supporting Evidence

  • Peak global Ecc Epi and Ecc Endo were decreased in all MI patients compared to normals.
  • Peak Ell strain was preserved in most infarcts except in LAD infarcts.
  • The best predictor of reduced LVEF in MI patients was reduced global Ecc Endo.

Takeaway

Doctors used a special MRI to see how well the heart works after a heart attack, finding that most parts of the heart still work well, except for some areas.

Methodology

Eighty patients with a history of myocardial infarction were assessed using feature tracking MRI to measure heart strain and compared to 60 healthy subjects.

Participant Demographics

Mean age was 64.4 years, with varying left ventricular ejection fractions and infarct sizes across different coronary territories.

Statistical Information

P-Value

p<0.0001

Statistical Significance

p<0.01

Digital Object Identifier (DOI)

10.1186/1532-429X-13-S1-P131

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