Cognitive Function in Hemodialysis Patients in Japan
Author Information
Author(s): Odagiri Gen, Sugawara Norio, Kikuchi Atsuhiro, Takahashi Ippei, Umeda Takashi, Saitoh Hisao, Yasui-Furukori Norio, Kaneko Sunao
Primary Institution: Hirosaki University School of Medicine
Hypothesis
What is the prevalence of cognitive impairment among hemodialysis patients and its relation to clinical characteristics?
Conclusion
There is a high prevalence of cognitive impairment among hemodialysis patients that adversely affects their hospitalization and life expectancy.
Supporting Evidence
- 18.8% of hemodialysis patients showed cognitive impairment based on the MMSE.
- Older hemodialysis patients had a higher prevalence of cognitive impairment.
- Education level was associated with MMSE scores among hemodialysis patients.
Takeaway
Many people on dialysis have trouble thinking clearly, which can make it harder for them to take care of their health.
Methodology
The study used a cross-sectional design and administered the Mini-Mental State Examination (MMSE) to 154 hemodialysis patients and 852 healthy controls.
Potential Biases
Potential bias due to the reliance on self-reported data and the limited scope of cognitive assessment.
Limitations
The study only used the MMSE for cognitive assessment and was cross-sectional, limiting causal inferences.
Participant Demographics
154 hemodialysis patients (88 males, 66 females) and 852 healthy volunteers (314 males, 538 females), aged 30 years and above.
Statistical Information
P-Value
0.001
Confidence Interval
95% CI 1.33 to 3.94
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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