Cactus Regulates Immune Response and Gut Microbiota in Mice
Author Information
Author(s): Kozai Hana, Watanabe Chihiro, Kosaka Rina, Aoki Takafumi, Hamada Hiroki, Kawashima Masato, Kono Takumi, Akagi Kosuke, Kremenik Michael J., Yano Hiromi, Tanaka Mamoru, Oyanagi Eri
Primary Institution: Kawasaki University of Medical Welfare
Hypothesis
Does a cactus-supplemented diet affect immune responses and gut microbiota in mice?
Conclusion
Cactus intake enhances immune function and gut health in mice.
Supporting Evidence
- Cactus intake increased plasma TNF-α and IgG antibody titers in mice.
- The NC group showed higher mucin content and IgA levels in feces.
- Lower levels of succinate and lactate were found in the NC group.
- Butyrate content was significantly higher in the NC group compared to cellulose.
- Changes in gut microbiota diversity were observed with cactus intake.
Takeaway
Eating cactus can help your body fight germs and keep your tummy healthy.
Methodology
Male C3H/HeN mice were divided into three diet groups: no fiber, cellulose, and cactus for 6 weeks, and immune responses were measured after LPS injection.
Limitations
The study did not evaluate T cell differentiation.
Participant Demographics
Nine-week-old male C3H/HeN mice.
Statistical Information
P-Value
p<0.01
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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