Measles Outbreaks in Lazio, Italy: The Role of Low Vaccine Coverage
Author Information
Author(s): Curtale Filippo, Perrelli Fabrizio, Mantovani Jessica, Ciofi degli Atti Marta, Filia Antonietta, Nicoletti Loredana, Magurano Fabio, Borgia Piero, Di Lallo Domenico
Primary Institution: Laziosanita' Agenzia di Sanita' Pubblica
Hypothesis
What are the sources and transmission routes of measles outbreaks in the Lazio region?
Conclusion
Low vaccine coverage communities pose a significant public health threat and require targeted immunization efforts.
Supporting Evidence
- 449 measles cases were reported during the outbreaks.
- Serotype D4 was likely imported from Romania and spread among the Roma/Sinti community.
- Low vaccine coverage in specific communities facilitated the outbreaks.
- 57% of cases required hospitalization during the outbreaks.
- Vaccination efforts were implemented in response to the outbreaks.
Takeaway
Some groups of people didn't get their measles shots, which allowed the disease to spread more easily. We need to help these groups get vaccinated.
Methodology
Data were collected from surveillance systems, field investigations, and molecular genotyping of the virus.
Limitations
Not all cases were genotyped, making it difficult to determine the exact number of cases in each outbreak.
Participant Demographics
The outbreaks primarily affected the Roma/Sinti population and Italian adolescents and adults.
Digital Object Identifier (DOI)
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