Biosynthesis, Characterization, and Antibacterial Activity of Gold, Silver, and Bimetallic Nanoparticles Using Annona squamosa L. Leaves
2024

Nanoparticles from Annona squamosa Leaves as Antibacterial Agents

publication 10 minutes Evidence: moderate

Author Information

Author(s): Jibrin Fatima, Fanoro Olufunto T., Maluleke Rodney, Lebepe Thabang C., Mgedle Nande, Mbaz Gracia It Mwad, Aladesuyi Olanrewaju A., Kalimuthu Rajendran, Odeku Oluwatoyin A., Oluwafemi Oluwatobi S.

Primary Institution: Pan African University Life and Earth Sciences Institute (PAULESI), University of Ibadan, University of Johannesburg

Hypothesis

Can silver, gold, and bimetallic nanoparticles synthesized from Annona squamosa leaves effectively combat pathogenic bacteria?

Conclusion

The study found that bimetallic nanoparticles showed significant antibacterial activity against Staphylococcus aureus and Escherichia coli.

Supporting Evidence

  • The synthesized nanoparticles were characterized to confirm their size and shape.
  • Bimetallic nanoparticles showed the lowest minimum inhibitory concentration against tested bacteria.
  • Green synthesis using plant extracts is an eco-friendly method for producing nanoparticles.

Takeaway

This study shows that tiny particles made from a plant can help fight germs that make us sick.

Methodology

The nanoparticles were synthesized using Annona squamosa leaf extract and characterized using various techniques including UV-Vis spectroscopy and TEM.

Limitations

The study did not explore the long-term stability of the nanoparticles or their effects in vivo.

Digital Object Identifier (DOI)

10.3390/antibiotics13121199

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