Zoledronic Acid for Pain Relief in Bone Tumors
Author Information
Author(s): Montella Liliana, Addeo Raffaele, Faiola Vincenzo, Cennamo Gregorio, Guarrasi Rosario, Capasso Elena, Mamone Rosanna, Michele Caraglia, Del Prete Salvatore
Primary Institution: Medical Oncology Unit 'San Giovanni di Dio' Hospital, Frattaminore, Naples, Italy
Hypothesis
Can zoledronic acid improve pain control in patients with metastatic chondrosarcoma and chordoma?
Conclusion
Zoledronic acid may significantly improve pain control in patients with bone tumors, regardless of tumor response to other treatments.
Supporting Evidence
- Zoledronic acid maintained pain control in the chondrosarcoma patient despite disease progression.
- The chordoma patient experienced significant pain reduction after starting zoledronic acid.
Takeaway
This study shows that a medicine called zoledronic acid can help people with certain bone tumors feel less pain, even if the tumors don't get smaller.
Methodology
Two case reports of patients treated with zoledronic acid for pain management.
Limitations
The study is based on only two case reports, limiting the generalizability of the findings.
Participant Demographics
One 63-year-old man with chondrosarcoma and one 66-year-old woman with chordoma.
Digital Object Identifier (DOI)
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